Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 4/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156966 | 0.89 | HPGD (0.41) | GSK3BDYRK1AMAP3K5KMT2AMEN1 | |
| SCHEMBL20141285 | 0.71 | KDM4E (0.40) | KDM4EKMT2AHPGDALDH1A1P2RX7 | |
| SCHEMBL19282175 | 0.67 | HTR3E (0.47) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL19559109 | 0.67 | FASN (0.54) | — | |
| SCHEMBL26125901 | 0.65 | PDCD1 (0.38) | GSK3BDYRK1AHPGD | |
| SCHEMBL3187202 | 0.65 | KDM4E (0.48) | KDM4EHPGDALDH1A1MAPTTDP1 | |
| SCHEMBL110825 | 0.64 | MGLL (0.42) | KDM4EKMT2AMEN1MGLLALDH1A1 | |
| SCHEMBL20036994 | 0.64 | KDM4E (0.43) | KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL20141817 | 0.64 | MAPT (0.40) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14863278 | 0.64 | HPGD (0.55) | GSK3BDYRK1AKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |