Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793581 | 0.83 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL746343 | 0.82 | ALDH1A1 (0.54) | ALDH1A1DRD2DRD3HTR2CLMNA | |
| SCHEMBL30164060 | 0.81 | ADRB1 (0.50) | ALDH1A1KDM4EDRD2DRD3HTR2C | |
| SCHEMBL30561225 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL30561230 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL20129616 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4ELMNAMEN1MAPT | |
| SCHEMBL20129624 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4E | |
| SCHEMBL26968319 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EDRD2DRD3LMNA | |
| SCHEMBL31122858 | 0.77 | HTR2C (0.51) | ALDH1A1KDM4EDRD2DRD3HTR2C | |
| SCHEMBL3639815 | 0.77 | HTR2C (0.51) | ALDH1A1KDM4EDRD2DRD3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056073-A1 | INDAZOLONE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 中国科学院上海药物研究所 | 2025-03-20 | — | — | WO | disclosed |
| CN-119613374-A | Indazolone compound, preparation method thereof, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-03-14 | — | — | CN | disclosed |
| CN-116669736-A | Fused heterocyclyl-substituted cyclohexanediimide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |