Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140928 | 0.76 | SLC6A7 (0.42) | KDM4EKMT2A | |
| SCHEMBL25267550 | 0.72 | MEN1 (0.36) | IDO1KMT2A | |
| SCHEMBL18759193 | 0.71 | GCK (0.39) | IDO1 | |
| SCHEMBL18759192 | 0.71 | GCK (0.39) | IDO1 | |
| SCHEMBL18759185 | 0.68 | MAPT (0.49) | ATMKMT2A | |
| SCHEMBL4589906 | 0.67 | PSMB5 (0.34) | IDO1 | |
| SCHEMBL4589908 | 0.67 | PSMB5 (0.34) | IDO1 | |
| SCHEMBL527703 | 0.66 | — | — | |
| SCHEMBL1503115 | 0.65 | GRM2 (0.60) | — | |
| SCHEMBL3624025 | 0.65 | AR (0.51) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |