Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 7/20 | 0.59 |
| ▸ | CDK2 | P24941 | 7/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142497 | 0.88 | CCNA2 (0.55) | CCNA2CDK2CDK5CDK5R1CCNE1 | |
| SCHEMBL20142841 | 0.88 | MAPT (0.63) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL20142267 | 0.86 | GSK3A (0.51) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL20142498 | 0.85 | CCNA2 (0.52) | CCNA2CDK2CDK5CDK5R1CCNE1 | |
| SCHEMBL20142387 | 0.84 | CCNA2 (0.81) | CCNA2CDK2CDK5CDK5R1CCNE1 | |
| SCHEMBL20142409 | 0.81 | GSK3A (0.53) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL20142179 | 0.81 | GSK3A (0.53) | CDK5CDK5R1NPC1ALDH1A1POLB | |
| SCHEMBL20142835 | 0.79 | GSK3A (0.57) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL20142420 | 0.79 | CDK5 (0.51) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL20142448 | 0.78 | GSK3A (0.73) | CCNA2CDK2CDK5CDK5R1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |