Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.56 |
| ▸ | CDK2 | P24941 | 3/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142267 | 0.89 | GSK3A (0.51) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142179 | 0.88 | GSK3A (0.53) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142409 | 0.88 | GSK3A (0.53) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142075 | 0.88 | CCNA2 (0.59) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142448 | 0.85 | GSK3A (0.73) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142417 | 0.84 | CCNA2 (0.57) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142835 | 0.84 | GSK3A (0.57) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142420 | 0.84 | CDK5 (0.51) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142253 | 0.82 | CCNA2 (0.82) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL20142502 | 0.80 | MEN1 (0.64) | MAPTNPC1RAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |