Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CCR2 | P41597 | 4/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742238 | 0.87 | ALDH1A1 (0.65) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL13305894 | 0.87 | CCR2 (0.69) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL13701158 | 0.87 | CCR2 (0.69) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL5254835 | 0.85 | CCR2 (0.67) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL1422436 | 0.84 | CCR2 (0.74) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL700800 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL6752492 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL20109879 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL7463101 | 0.81 | CCR2 (0.71) | ALDH1A1CYP1A2POLBCCR2MCL1 | |
| SCHEMBL10757133 | 0.81 | ALDH1A1 (0.66) | ALDH1A1CYP1A2POLBCCR2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |