Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 6/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014316 | 0.90 | HCRTR1 (0.55) | HCRTR1HCRTR2OPRM1NPC1RAB9A | |
| SCHEMBL2014309 | 0.88 | HCRTR1 (0.57) | HCRTR1HCRTR2OPRM1NPC1RAB9A | |
| SCHEMBL2012177 | 0.87 | HCRTR1 (0.58) | HCRTR1HCRTR2OPRM1NPC1RAB9A | |
| SCHEMBL2015404 | 0.87 | HCRTR1 (0.57) | HCRTR1HCRTR2OPRM1NPC1RAB9A | |
| SCHEMBL2017397 | 0.86 | HCRTR1 (0.57) | HCRTR1HCRTR2OPRM1NPC1RAB9A | |
| SCHEMBL2010539 | 0.83 | HCRTR1 (0.63) | HCRTR1HCRTR2NPC1RAB9AHPGD | |
| SCHEMBL2012310 | 0.82 | HCRTR1 (0.67) | HCRTR1HCRTR2NPC1RAB9ADRD3 | |
| SCHEMBL2013416 | 0.82 | HCRTR1 (0.60) | HCRTR1HCRTR2OPRM1NPC1RAB9A | |
| SCHEMBL13139060 | 0.82 | HCRTR1 (0.77) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2014249 | 0.82 | HCRTR1 (0.61) | HCRTR1HCRTR2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |