Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.61 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HAT1 | O14929 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012168 | 0.90 | HCRTR1 (0.63) | HCRTR1HCRTR2NPC1RAB9AHRH3 | |
| SCHEMBL6918074 | 0.86 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9AKDM4E | |
| SCHEMBL2014627 | 0.86 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9AKDM4E | |
| SCHEMBL13139060 | 0.83 | HCRTR1 (0.77) | HCRTR1HCRTR2NPC1RAB9AHRH3 | |
| SCHEMBL2014124 | 0.82 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2014229 | 0.82 | HCRTR1 (0.58) | HCRTR1HCRTR2NPC1RAB9AKDM4E | |
| SCHEMBL2012310 | 0.81 | HCRTR1 (0.67) | HCRTR1HCRTR2NPC1RAB9AHRH3 | |
| SCHEMBL2013183 | 0.81 | HCRTR1 (0.61) | HCRTR1HCRTR2NPC1RAB9AHRH3 | |
| SCHEMBL2012749 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2NPC1RAB9AALDH1A1 | |
| SCHEMBL2051297 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2NPC1RAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |