Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 6/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513273 | 0.88 | PDK4 (0.64) | PDK4GPR119TBK1NAMPTGRM5 | |
| SCHEMBL3642418 | 0.81 | PDK4 (0.55) | PDK4GPR119NAMPTGRM5GRM1 | |
| SCHEMBL26074064 | 0.81 | PDK4 (0.55) | PDK4GPR119NAMPTGRM5GRM1 | |
| SCHEMBL31120842 | 0.81 | PDK4 (0.55) | PDK4GPR119NAMPTGRM5GRM1 | |
| SCHEMBL20141605 | 0.80 | KMT2A (0.42) | — | |
| SCHEMBL24984469 | 0.80 | TBK1 (0.43) | PDK4GPR119TBK1NAMPTGRM5 | |
| SCHEMBL25831860 | 0.80 | GPR119 (0.47) | PDK4GPR119TBK1NAMPTGRM5 | |
| SCHEMBL30163921 | 0.80 | TBK1 (0.43) | PDK4GPR119TBK1NAMPTGRM5 | |
| SCHEMBL25044030 | 0.80 | PDK4 (0.54) | PDK4GPR119NAMPTGRM5GRM1 | |
| SCHEMBL31159182 | 0.79 | GPR119 (0.48) | PDK4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |