Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637480 | 0.86 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2SCD5TAS1R3TAS1R1 | |
| SCHEMBL20142327 | 0.80 | PDK4 (0.52) | — | |
| SCHEMBL27791716 | 0.77 | ALOX15 (0.38) | KMT2ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7396701 | 0.73 | KMT2A (0.46) | KMT2ASMN1; SMN2ALDH1A1MEN1NPC1 | |
| Bicarbonate SCHEMBL7256331 | 0.71 | ESR2 (0.55) | ESR2GRIA2GRIA4ALDH1A1KDM4E | |
| SCHEMBL1513273 | 0.71 | PDK4 (0.64) | — | |
| SCHEMBL28510941 | 0.68 | CNR1 (0.40) | KMT2ASMN1; SMN2SCD5ALDH1A1KDM4E | |
| SCHEMBL16114190 | 0.67 | ALDH1A1 (0.48) | KMT2ASMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL5369598 | 0.66 | GRM5 (0.60) | TP53 | |
| SCHEMBL19926374 | 0.66 | NAMPT (0.50) | KMT2ASMN1; SMN2TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |