Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140757 | 0.87 | GRIN2B (0.44) | GRM1DGAT2DRD3ACACB | |
| SCHEMBL27128220 | 0.82 | GRM1 (0.52) | GRM1DRD2DRD3 | |
| SCHEMBL4524209 | 0.80 | HTR3E (0.47) | GRM1DRD3SLC6A7ACACB | |
| SCHEMBL4531399 | 0.77 | CHRM4 (0.51) | GRM1ALOX5TTRDGAT2DRD3 | |
| SCHEMBL27130857 | 0.77 | NOTUM (0.48) | LMNADRD2DRD3SLC6A7MEN1 | |
| SCHEMBL5652856 | 0.75 | GRIN2D (0.42) | GRM1LMNAMEN1KMT2A | |
| SCHEMBL15205472 | 0.74 | CHRM4 (0.42) | GRM1ACACBKMT2A | |
| SCHEMBL20142342 | 0.74 | NOTUM (0.51) | RIPK1LMNADRD2DRD3SLC6A7 | |
| SCHEMBL22581659 | 0.74 | CHRM2 (0.41) | ACACB | |
| SCHEMBL27131408 | 0.73 | MAPT (0.40) | RIPK1FFAR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |