Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.45 |
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142501 | 0.90 | CDK5 (0.49) | ADORA3ADORA2AADORA1DHODHMAPT | |
| SCHEMBL20142452 | 0.86 | NPC1 (0.50) | EPHX2ADORA3ADORA2AADORA1DHODH | |
| SCHEMBL20142502 | 0.84 | MEN1 (0.64) | ADORA3ADORA2AADORA1DHODHMAPT | |
| SCHEMBL20142497 | 0.83 | CCNA2 (0.55) | ADORA3ADORA2AADORA1DHODHMAPT | |
| SCHEMBL20141966 | 0.83 | MAPT (0.66) | MAPTNPC1MEN1KMT2ARAB9A | |
| SCHEMBL20142504 | 0.80 | CCNA2 (0.49) | ADORA3ADORA2AADORA1DHODHMAPT | |
| SCHEMBL20142105 | 0.80 | CDK5 (0.67) | MAPTNPC1MEN1KMT2ARAB9A | |
| SCHEMBL20142841 | 0.78 | MAPT (0.63) | ADORA3ADORA2AADORA1MAPTNPC1 | |
| SCHEMBL20142465 | 0.78 | CDK5 (0.52) | ADORA3ADORA2AADORA1DHODHMAPT | |
| SCHEMBL20142402 | 0.78 | NPC1 (0.57) | DHODHMAPTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |