Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584762 | 0.88 | CKS1B (0.46) | CKS1BSKP1SKP2BACE1ALDH1A1 | |
| SCHEMBL20142485 | 0.80 | MAPT (0.49) | ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL4863963 | 0.80 | CHRM2 (0.48) | CKS1BSKP1SKP2BACE1ALDH1A1 | |
| SCHEMBL5202415 | 0.80 | HTR6 (0.52) | CKS1BSKP1SKP2BACE1GPR119 | |
| SCHEMBL26099409 | 0.80 | GPR119 (0.46) | MAPTGPR119NAMPTPOLB | |
| SCHEMBL4558301 | 0.79 | BACE1 (0.59) | CKS1BSKP1SKP2BACE1ALDH1A1 | |
| SCHEMBL6588562 | 0.78 | BACE1 (0.46) | CKS1BSKP1SKP2BACE1ALDH1A1 | |
| SCHEMBL26842219 | 0.78 | BACE1 (0.44) | CKS1BSKP1SKP2BACE1ALDH1A1 | |
| SCHEMBL5366552 | 0.77 | TP53 (0.49) | CKS1BSKP1SKP2BACE1ALDH1A1 | |
| SCHEMBL14395343 | 0.76 | DRD2 (0.49) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |