Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20029254 | 0.90 | ALDH1A1 (0.60) | ALDH1A1POLBKMT2ASLC6A2SLC6A3 | |
| SCHEMBL9363349 | 0.89 | POLB (0.73) | ALDH1A1POLBKMT2ASLC6A2SLC6A3 | |
| SCHEMBL11057368 | 0.89 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2ASLC6A2SLC6A3 | |
| SCHEMBL20029258 | 0.85 | MGLL (0.56) | ALDH1A1POLBKMT2ARAB9AGAA | |
| SCHEMBL20023001 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ATDP1RAB9A | |
| SCHEMBL20029246 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KMT2ARAB9AGAAEPHX2 | |
| SCHEMBL20029049 | 0.82 | MGLL (0.59) | ALDH1A1KMT2ARAB9AGAAMGLL | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.81 | POLB (0.78) | ALDH1A1POLBRAB9AMGLLLMNA | |
| SCHEMBL27144 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL23994825 | 0.80 | TDP1 (0.55) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11660280-B2 | Treatment of drug resistant gliomas | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2023-05-30 | — | — | US | disclosed |
| US-11084852-B2 | Ubiquitin interacting motif peptides as therapeutics | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200215015-A1 | TREATMENT OF DRUG RESISTANT GLIOMAS | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2020-07-09 | — | — | US | disclosed |
| US-10398659-B2 | Adjuvant chemotherapy for anaplastic gliomas | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2019-09-03 | — | — | US | disclosed |
| WO-2019060152-A1 | TREATMENT OF DRUG RESISTANT GLIOMAS | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2019-03-28 | — | — | WO | disclosed |
| US-9968569-B2 | Adjuvant chemotherapy for anaplastic gliomas | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2018-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084852-B2 | Ubiquitin interacting motif peptides as therapeutics | UBXN1, UBQLN1, UFM1 | ALDH1A1 4400/4885POLB 2216/4885KMT2A 2691/4885 |
| US-20200215015-A1 | TREATMENT OF DRUG RESISTANT GLIOMAS | MGMT, NES, DCX | ALDH1A1 1343/4885POLB 1018/4885KMT2A 1384/4885 |
| US-11660280-B2 | Treatment of drug resistant gliomas | MGMT, NES, DCX | ALDH1A1 1343/4885POLB 1018/4885KMT2A 1384/4885 |
| US-10398659-B2 | Adjuvant chemotherapy for anaplastic gliomas | TRIB2, NES, DCX | ALDH1A1 271/4885POLB 2333/4885KMT2A 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.