SCHEMBL20143412

SCHEMBL20143412

CCCCc1ccc2c(-c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)c3ccccc3c(-c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
RORA P35398 2/20 0.40
RORC P51449 2/20 0.40
RORB Q92753 2/20 0.40
TSPO P30536 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPK8 P45983 1/20 0.40
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
CNR2 P34972 2/20 0.36
FDFT1 P37268 2/20 0.36
HSD11B1 P28845 1/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
PTGER4 P35408 1/20 0.36
PGR P06401 2/20 0.36
PLA2G4A P47712 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262654 0.94 KDM4E (0.41) KDM4ERORARORCRORBTSPO
SCHEMBL262751 0.94 TSPO (0.43) KDM4ERORARORCRORBTSPO
SCHEMBL262161 0.94 TSPO (0.43) KDM4ERORARORCRORBTSPO
SCHEMBL262441 0.94 KDM4E (0.41) KDM4ERORARORCRORBTSPO
SCHEMBL25658235 0.94 HSD11B1 (0.40) KDM4ERORARORCRORBTSPO
SCHEMBL262517 0.92 RORA (0.42) KDM4ERORARORCRORBTSPO
SCHEMBL262206 0.92 EP300 (0.43) RORARORCRORBTSPOMAPK8
SCHEMBL261799 0.90 HSD11B1 (0.44) KDM4ERORARORCRORBTSPO
SCHEMBL262526 0.90 HSD11B1 (0.44) KDM4ERORARORCRORBTSPO
SCHEMBL10161081 0.89 MAPK8 (0.38) RORARORCRORBTSPOMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972790-B2 Anthracene derivative, and light-emitting material, light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-15 US disclosed