SCHEMBL20143511

SCHEMBL20143511

Cc1nc2ccccc2n1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.55
MAPK1 P28482 1/20 0.55
TSHR P16473 2/20 0.52
LMNA P02545 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
TNF P01375 1/20 0.50
KDM4E B2RXH2 1/20 0.50
TP53 P04637 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
HSD17B10 Q99714 1/20 0.50
GALR3 O60755 3/20 0.49
NR2F2 P24468 3/20 0.49
RAB9A P51151 2/20 0.47
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
ALDH3A1 P30838 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353890 0.76 SMN1; SMN2 (0.63) HTTMAPK1TSHRLMNASMN1; SMN2
SCHEMBL248853 0.76 SMN1; SMN2 (0.42) HTTMAPK1TSHRLMNASMN1; SMN2
SCHEMBL4027582 0.74 SMN1; SMN2 (0.61) HTTMAPK1LMNASMN1; SMN2TNF
SCHEMBL5144258 0.74 NOS2 (0.61) HTTMAPK1TSHRLMNASMN1; SMN2
SCHEMBL13839193 0.74 HTT (0.55) HTTMAPK1TSHRLMNASMN1; SMN2
SCHEMBL8422526 0.74 HTT (0.55) HTTMAPK1TSHRLMNASMN1; SMN2
SCHEMBL19044352 0.74 SMN1; SMN2 (0.41) HTTMAPK1TSHRLMNASMN1; SMN2
SCHEMBL18347137 0.74 HTT (0.55) HTTMAPK1TSHRLMNASMN1; SMN2
Iodide SCHEMBL336205 0.74 SMN1; SMN2 (0.61) HTTMAPK1TSHRLMNASMN1; SMN2
Bromide SCHEMBL5318089 0.74 SMN1; SMN2 (0.61) HTTMAPK1TSHRLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-10727418-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-28 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-9972789-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-15 US disclosed