Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344786 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2NOS2ATMNPC1ALDH1A1 | |
| SCHEMBL19591078 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2NOS2ATMNPC1ALDH1A1 | |
| SCHEMBL4027582 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2NOS2ATMNPC1ALDH1A1 | |
| SCHEMBL2105815 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2ATMNPC1ALDH1A1RAB9A | |
| SCHEMBL28295720 | 0.76 | NOS2 (0.61) | SMN1; SMN2NOS2NPC1RAB9APKM | |
| SCHEMBL20143511 | 0.76 | HTT (0.55) | SMN1; SMN2NPC1ALDH1A1RAB9ATP53 | |
| SCHEMBL19044352 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2NOS2ATMNPC1ALDH1A1 | |
| SCHEMBL18083403 | 0.74 | TSHR (0.50) | SMN1; SMN2NOS2ATMNPC1ALDH1A1 | |
| SCHEMBL15835577 | 0.72 | MAPK1 (0.61) | NOS2ATMALDH1A1TSHRUSP2 | |
| SCHEMBL31061815 | 0.72 | MAPK1 (0.61) | NOS2ATMALDH1A1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003329-B | T-type benzimidazole third-order nonlinear optical material, and preparation method and application thereof | 浙江工业大学 | 2024-09-24 | — | — | CN | claimed |
| CN-114805215-B | Fluorescent sensing material, preparation method thereof and application of fluorescent sensing material in aspect of detecting nerve agent with high sensitivity | 中国科学院化学研究所 | 2023-11-28 | — | — | CN | claimed |
| CN-116003329-A | T-type benzimidazole third-order nonlinear optical material, and preparation method and application thereof | 浙江工业大学 | 2023-04-25 | — | — | CN | claimed |
| CN-114805215-A | Fluorescent sensing material, preparation method thereof and application of fluorescent sensing material in high-sensitivity detection of nerve toxicant | 中国科学院化学研究所 | 2022-07-29 | — | — | CN | claimed |
| CN-114805215-B | Fluorescent sensing material, preparation method thereof and application of fluorescent sensing material in aspect of detecting nerve agent with high sensitivity | 中国科学院化学研究所 | 2023-11-28 | — | — | CN | disclosed |
| CN-114805215-A | Fluorescent sensing material, preparation method thereof and application of fluorescent sensing material in high-sensitivity detection of nerve toxicant | 中国科学院化学研究所 | 2022-07-29 | — | — | CN | disclosed |
| US-20130131344-A1 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHODS OF MAKING SAME | BASF SE (DE) | 2013-05-23 | — | — | US | disclosed |
| EP-2533898-A2 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHOD OF MAKING SAME | The Regents of the University of California (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20120259117-A1 | ORGANO-METALLIC FRAMEWORKS AND METHODS OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-10-11 | — | — | US | disclosed |
| EP-2443133-A2 | ORGANO-METALLIC FRAMEWORKS AND METHODS OF MAKING SAME | The Regents of The University of California (US) | 2012-04-25 | — | — | EP | disclosed |
| WO-2011146155-A9 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHOD OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011146155-A2 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHOD OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2010148374-A2 | ORGANO-METALLIC FRAMEWORKS AND METHODS OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-23 | — | — | WO | disclosed |
| US-7651746-B2 | Halogenated bisdiarylaminopolycyclic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | US | disclosed |
| WO-2005049546-A1 | HALOGENATED BISDIARYLAMINOPOLYCYLIC AROMATIC COMPOUNDS AND POLYMERS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259117-A1 | ORGANO-METALLIC FRAMEWORKS AND METHODS OF MAKING SAME | HNRNPF, EPCAM, YTHDF2 | SMN1; SMN2 469/4885NOS2 675/4885ATM 1605/4885 |
| US-20130131344-A1 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHODS OF MAKING SAME | CA6, GZMB, PMS2 | SMN1; SMN2 2277/4885NOS2 1278/4885ATM 3412/4885 |
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | AHR, AADAC, ARNT | SMN1; SMN2 4864/4885NOS2 3595/4885ATM 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.