Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085936 | 0.83 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GALDH1A1LMNA | |
| SCHEMBL12575507 | 0.81 | LMNA (0.39) | EHMT2EHMT1APOBEC3GALDH1A1DUT | |
| SCHEMBL409623 | 0.79 | EHMT2 (0.53) | EHMT2EHMT1APOBEC3GALDH1A1LMNA | |
| SCHEMBL11821480 | 0.78 | EHMT2 (0.57) | EHMT2EHMT1APOBEC3GALDH1A1LMNA | |
| SCHEMBL10326593 | 0.77 | EHMT2 (0.55) | EHMT2EHMT1APOBEC3GALDH1A1LMNA | |
| SCHEMBL21111946 | 0.77 | HDAC1 (0.46) | ALDH1A1LMNARAB9ANPC1KMT2A | |
| SCHEMBL12337472 | 0.76 | EHMT2 (0.50) | EHMT2EHMT1APOBEC3GALDH1A1LMNA | |
| SCHEMBL11833495 | 0.76 | EHMT2 (0.70) | EHMT2EHMT1APOBEC3GALDH1A1LMNA | |
| SCHEMBL21320645 | 0.75 | EHMT2 (0.53) | EHMT2EHMT1APOBEC3GALDH1A1LMNA | |
| SCHEMBL18622527 | 0.75 | LMNA (0.44) | EHMT2EHMT1APOBEC3GALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968686-B2 | Antisense oligonucleotides with improved pharmacokinetic properties | UNIVERSITY OF VIENNA (AT) | 2018-05-15 | — | — | US | disclosed |