SCHEMBL409623

SCHEMBL409623

COCCSSc1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.53
EHMT1 Q9H9B1 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
RAB9A P51151 7/20 0.40
NPC1 O15118 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
TP53 P04637 2/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 4/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
POLB P06746 1/20 0.37
MAPT P10636 2/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195622 0.91 EHMT2 (0.47) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL31456218 0.91 EHMT2 (0.47) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL23571163 0.90 EHMT2 (0.50) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL12421905 0.87 EHMT2 (0.47) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL11821480 0.86 EHMT2 (0.57) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL12085936 0.85 EHMT2 (0.52) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL10326593 0.84 EHMT2 (0.55) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL10326588 0.84 EHMT2 (0.43) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL12337472 0.83 EHMT2 (0.50) EHMT2EHMT1APOBEC3GRAB9ANPC1
SCHEMBL11833495 0.83 EHMT2 (0.70) EHMT2EHMT1APOBEC3GRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323028-A1 ADHESIVE PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2023-10-12 US disclosed
US-20230323028-A1 ADHESIVE PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2023-10-12 US disclosed
WO-2023191209-A1 MICELLE INCLUDING HYDROPHILIC PEPTIDE AND USE THEREOF 주식회사 퓨전바이오텍 2023-10-05 WO disclosed
US-10543280-B2 Stabilization of biomolecules using sugar polymers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-01-28 US disclosed
US-20190125885-A1 STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-05-02 US disclosed
US-9901648-B2 Stabilization of biomolecules using sugar polymers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-27 US disclosed
US-9433684-B2 Conjugates of small-interfering nucleic acids NEKTAR THERAPEUTICS (US) 2016-09-06 US disclosed
US-20150232616-A1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES, INC. 2015-08-20 US disclosed
US-9089610-B2 Complexes of small-interfering nucleic acids NEKTAR THERAPEUTICS (US) 2015-07-28 US disclosed
US-8980326-B2 Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents INTEZYNE TECHNOLOGIES, INC. (US) 2015-03-17 US disclosed
US-8426477-B1 Polymeric micelles for drug delivery INTEZYNE TECHNOLOGIES, LLC (US) 2013-04-23 US disclosed
US-8268936-B2 Synthesis of hybrid block copolymers and uses thereof INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-18 US disclosed
US-8263663-B2 Azide functionalized peptide targeting groups INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-11 US disclosed
US-20120100096-A1 CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS NEKTAR THERAPEUTICS (US) 2012-04-26 US disclosed
US-20120064061-A1 ADHESIVE COMPOSITION COMPRISING TANNIN, POLY(ETHYLENE GLYCOL), AND WATER, LOWER ALCOHOL OR MIXTURE THEREOF INNOTHERAPY INC. (KR) 2012-03-15 US disclosed
US-20110213013-A1 Complexes of Small-Interfering Nucleic Acids NEKTAR THERAPEUTICS (US) 2011-09-01 US disclosed
US-20110124840-A1 Synthesis of Homopolymers and Block Copolymers INTEZYNE TECHNOLOGIES, INC. 2011-05-26 US disclosed
US-20110092668-A1 AZIDE FUNCTIONALIZED PEPTIDE TARGETING GROUPS INTEZYNE TECHNOLOGIES, INC. (US) 2011-04-21 US disclosed
US-20110091534-A1 COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY INTEZYNE TECHNOLOGIES, INC. (US) 2011-04-21 US disclosed
US-20110021718-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF INTEZYNE TECHNOLOGIES (US) 2011-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230323028-A1 ADHESIVE PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF ICAM1, CDH1, VCAM1 EHMT2 721/4885EHMT1 527/4885APOBEC3G 1544/4885
US-20120064061-A1 ADHESIVE COMPOSITION COMPRISING TANNIN, POLY(ETHYLENE GLYCOL), AND WATER, LOWER ALCOHOL OR MIXTURE THEREOF EPCAM, ICAM1, VCAM1 EHMT2 944/4885EHMT1 473/4885APOBEC3G 3640/4885
US-20110124840-A1 Synthesis of Homopolymers and Block Copolymers PARG, PCNA, PARN EHMT2 2823/4885EHMT1 3375/4885APOBEC3G 1039/4885
US-20110092668-A1 AZIDE FUNCTIONALIZED PEPTIDE TARGETING GROUPS IAPP, NGLY1, MSN EHMT2 4557/4885EHMT1 4654/4885APOBEC3G 2323/4885
US-20110091534-A1 COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY ABCB4, ABCB11, CLTB EHMT2 4062/4885EHMT1 4092/4885APOBEC3G 4102/4885
US-10543280-B2 Stabilization of biomolecules using sugar polymers TREH, HBG1, SMURF1 EHMT2 4185/4885EHMT1 3780/4885APOBEC3G 2787/4885
US-20190125885-A1 STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS TREH, HBG1, SMURF1 EHMT2 4185/4885EHMT1 3780/4885APOBEC3G 2787/4885
US-20120100096-A1 CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS SLC19A1, FOLR1, SLC46A1 EHMT2 2504/4885EHMT1 2680/4885APOBEC3G 2436/4885
US-20110213013-A1 Complexes of Small-Interfering Nucleic Acids SNRPA, NSUN2, SNRPE EHMT2 3206/4885EHMT1 3383/4885APOBEC3G 1741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.