Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22698598 | 0.87 | HDAC8 (0.51) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15702071 | 0.86 | SSTR3 (0.45) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15704359 | 0.82 | HDAC8 (0.46) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16847583 | 0.81 | HDAC8 (0.55) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15702064 | 0.80 | SSTR3 (0.52) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18683438 | 0.79 | PLA2G2A (0.40) | — | |
| SCHEMBL12836787 | 0.79 | SIRT5 (0.39) | HDAC8HDAC1SIRT2SIRT1CALCRL | |
| SCHEMBL15702069 | 0.79 | SSTR3 (0.51) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26066853 | 0.78 | HDAC8 (0.39) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26066857 | 0.78 | HDAC8 (0.39) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968647-B2 | Small molecule conjugates for intracellular delivery of biologically active compounds | HOFFMANN-LA ROCHE INC. (US) | 2018-05-15 | — | — | US | disclosed |