Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143907 | 0.96 | TSHR (0.40) | TSHRPTAFRMAPTALDH1A1KDM4E | |
| SCHEMBL20143908 | 0.91 | TSHR (0.36) | TSHR | |
| SCHEMBL18104303 | 0.89 | TSHR (0.41) | TSHRMAPTHTR1DADRA1AALDH1A1 | |
| SCHEMBL20143912 | 0.89 | TSHR (0.35) | TSHRKIF11HTR1DADRA1AALDH1A1 | |
| SCHEMBL18104319 | 0.89 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL18104291 | 0.84 | ALDH1A1 (0.34) | TSHRALDH1A1KDM4ETP53 | |
| SCHEMBL13322025 | 0.84 | TSHR (0.48) | TSHRPTAFRMAPTKDM4ETP53 | |
| SCHEMBL20143911 | 0.83 | KIF11 (0.38) | TSHRKIF11PTAFRMAPTHTR1D | |
| SCHEMBL17807601 | 0.81 | TSHR (0.50) | TSHRPTAFRMAPTALDH1A1HCRTR2 | |
| SCHEMBL12422878 | 0.81 | TDP1 (0.37) | TSHRMAPTHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9972783-B2 | High energy triarylamine compounds for hole transport materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-15 | — | — | US | disclosed |