Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18104301 | 0.85 | HSD17B1 (0.36) | PTAFRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20143910 | 0.83 | TSHR (0.37) | KIF11PTAFRKDM4EALDH1A1MAPT | |
| SCHEMBL21173573 | 0.83 | TSHR (0.41) | PTAFRKDM4EALDH1A1MEN1LMNA | |
| SCHEMBL20143912 | 0.82 | TSHR (0.35) | KIF11KDM4EALDH1A1LMNAHTR1D | |
| SCHEMBL13358327 | 0.80 | NR1H2 (0.39) | KIF11PTAFRKDM4EALDH1A1MEN1 | |
| SCHEMBL20143908 | 0.80 | TSHR (0.36) | TSHR | |
| SCHEMBL7154196 | 0.79 | ACHE (0.39) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL13929896 | 0.79 | ACHE (0.39) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL20143907 | 0.78 | TSHR (0.40) | PTAFRKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL16573897 | 0.78 | RAB9A (0.37) | KIF11KDM4EALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9972783-B2 | High energy triarylamine compounds for hole transport materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-15 | — | — | US | disclosed |