Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | F13A1 | P00488 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ESRRG | P62508 | 4/20 | 0.53 |
| ▸ | ESRRB | O95718 | 3/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160340 | 0.82 | ESRRG (0.54) | KDM4EF13A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14370357 | 0.82 | KDM4E (0.69) | KDM4EF13A1GAANPC1CYP1A2 | |
| SCHEMBL159162 | 0.82 | CA12 (0.63) | NPC1MAPTRAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL1437502 | 0.82 | KDM4E (0.69) | KDM4EF13A1GAANPC1CYP1A2 | |
| SCHEMBL23700596 | 0.81 | KDM4E (0.62) | KDM4EF13A1GAANPC1CYP1A2 | |
| SCHEMBL19216397 | 0.80 | KDM4E (0.67) | KDM4EF13A1GAANPC1CYP1A2 | |
| SCHEMBL734658 | 0.80 | KDM4E (1.00) | KDM4EF13A1GAANPC1CYP1A2 | |
| SCHEMBL19216398 | 0.80 | KDM4E (0.67) | KDM4EF13A1GAANPC1CYP1A2 | |
| SCHEMBL4161209 | 0.78 | ESRRB (0.77) | KDM4EF13A1GAANPC1CYP1A2 | |
| SCHEMBL2379821 | 0.78 | KDM4E (0.65) | KDM4EF13A1GAANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2831587-B1 | SIGNALING CONJUGATES AND METHODS OF USE | VENTANA MED SYST INC (US) | 2018-05-16 | — | — | EP | disclosed |