SCHEMBL160340

SCHEMBL160340

Nc1ccc(CCNC(=O)S)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 1/20 0.54
GFER P55789 1/20 0.48
HIF1A Q16665 1/20 0.47
KDM4E B2RXH2 1/20 0.46
F13A1 P00488 1/20 0.46
PPID Q08752 1/20 0.46
ST14 Q9Y5Y6 1/20 0.45
CA2 P00918 5/20 0.43
CA1 P00915 4/20 0.43
CA9 Q16790 4/20 0.43
CA12 O43570 3/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15940162 0.84 ESRRG (0.57) ESRRGGFERHIF1AKDM4EF13A1
SCHEMBL625333 0.82 ESRRG (0.55) ESRRGGFERHIF1AKDM4EF13A1
SCHEMBL20144285 0.82 KDM4E (0.67) ESRRGGFERKDM4EF13A1SMN1; SMN2
SCHEMBL915701 0.82 ESRRG (0.55) ESRRGGFERHIF1AKDM4EF13A1
SCHEMBL2715966 0.81 KDM4E (0.70) ESRRGGFERHIF1AKDM4EF13A1
SCHEMBL12532995 0.81 ESRRG (0.58) ESRRGGFERHIF1AKDM4EF13A1
SCHEMBL159162 0.80 CA12 (0.63) CA2CA1CA9CA12SMN1; SMN2
SCHEMBL6850677 0.79 ESRRG (0.53) ESRRGGFERHIF1APPIDST14
SCHEMBL22403771 0.79 HPGD (0.54) ESRRGPPIDST14CA2CA1
SCHEMBL6415918 0.79 CA1 (0.66) ESRRGGFERHIF1APPIDST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-20150327552-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2015-11-19 US disclosed
US-9125408-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2015-09-08 US disclosed
US-8884022-B2 Inhibition of bacterial biofilms with aryl carbamates NORTH CAROLINA STATE UNIVERSITY (US) 2014-11-11 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
WO-2012030986-A2 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY (US) 2012-03-08 WO disclosed
WO-2012006276-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT ESRRG 2453/4885GFER 190/4885HIF1A 3351/4885
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT ESRRG 2453/4885GFER 190/4885HIF1A 3351/4885
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES PGLS, BLVRB, AADAC ESRRG 2209/4885GFER 44/4885HIF1A 3404/4885
US-20150327552-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT ESRRG 2453/4885GFER 190/4885HIF1A 3351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.