SCHEMBL20144600

SCHEMBL20144600

CC(C)CCNC(=O)CC(C)(C)OCCC(C)(C)NC(=O)C(C)(C)C(C)(C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.31
PKM P14618 1/20 0.31
PGA5 P0DJD9 2/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20144623 0.89 HPGD (0.33) HPGDMEN1MAPTKMT2ALMNA
SCHEMBL20144531 0.83 PGA5 (0.31) HPGDMEN1MAPTKMT2APGA5
SCHEMBL20144512 0.81 HPGD (0.36) HPGDMEN1MAPTKMT2ALMNA
SCHEMBL20144585 0.76 HPGD (0.31) HPGD
SCHEMBL20144537 0.74 TP53 (0.33) HPGDKMT2ASMN1; SMN2
SCHEMBL25843957 0.68 CNR1 (0.34)
SCHEMBL20144602 0.67 ANPEP (0.32) HPGD
SCHEMBL14767469 0.67 CHRNB2 (0.35) HPGDPGA5SMN1; SMN2
SCHEMBL18389590 0.67
SCHEMBL24340832 0.66 MEN1 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3321279-B1 EXENATIDE MODIFIER AND USE THEREOF BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) 2020-02-12 EP disclosed
EP-3321279-A1 EXENATIDE MODIFIER AND USE THEREOF Bright Gene Bio-Medical Technology Co., Ltd. (CN) 2018-05-16 EP disclosed