Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PGA5 | P0DJD9 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144578 | 0.82 | TP53 (0.37) | HPGDKMT2ASMN1; SMN2GAAHTT | |
| SCHEMBL20144600 | 0.81 | HPGD (0.34) | HPGDKMT2AMEN1MAPTLMNA | |
| SCHEMBL20144623 | 0.80 | HPGD (0.33) | HPGDKMT2AMEN1MAPTLMNA | |
| SCHEMBL20144531 | 0.79 | PGA5 (0.31) | HPGDKMT2AMEN1MAPTPGA5 | |
| SCHEMBL22803189 | 0.75 | KMT2A (0.33) | KMT2AMEN1CYP2C19 | |
| SCHEMBL15462687 | 0.74 | — | — | |
| SCHEMBL26593066 | 0.73 | MAPK1 (0.35) | — | |
| SCHEMBL14767469 | 0.73 | CHRNB2 (0.35) | HPGDSMN1; SMN2PGA5CNR1 | |
| SCHEMBL24805287 | 0.72 | EPHX2 (0.32) | MAPT | |
| SCHEMBL13848317 | 0.71 | LMNA (0.42) | HPGDKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321279-A1 | EXENATIDE MODIFIER AND USE THEREOF | Bright Gene Bio-Medical Technology Co., Ltd. (CN) | 2018-05-16 | — | — | EP | disclosed |