SCHEMBL20144609

SCHEMBL20144609

COc1ccc(/C=C(\C=O)OC=O)c(OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
CYP1A2 P05177 9/20 0.53
CYP1A1 P04798 7/20 0.53
CYP1B1 Q16678 7/20 0.53
MAPT P10636 4/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
CYP3A4 P08684 3/20 0.50
CYP2C9 P11712 2/20 0.50
LY96 Q9Y6Y9 1/20 0.48
NFE2L2 Q16236 2/20 0.47
TNFRSF1A P19438 1/20 0.47
GAA P10253 1/20 0.46
CYP2C19 P33261 2/20 0.45
CYP2E1 P05181 1/20 0.45
CYP2C8 P10632 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2A6 P11509 1/20 0.45
CYP4B1 P13584 1/20 0.45
CYP2B6 P20813 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909563 0.80 ALDH1A1 (0.64) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
SCHEMBL14040393 0.76 LY96 (0.52) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
SCHEMBL12014040 0.75 LY96 (0.48) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
SCHEMBL27567539 0.75 CYP1A2 (0.66) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
SCHEMBL96291 0.75 ALDH1A1 (1.00) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
SCHEMBL7192327 0.74 CYP1A2 (0.63) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
Hydrochloric Acid SCHEMBL9456784 0.73 ALDH1A1 (0.96) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
SCHEMBL5378571 0.73 MAPT (0.59) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
SCHEMBL14462722 0.72 ALDH1A1 (0.58) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT
Formaldehyde SCHEMBL28854145 0.72 ALDH1A1 (0.92) ALDH1A1CYP1A2CYP1A1CYP1B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102708-B1 CURABLE COMPOSITION, COLOR FILTER, AND MANUFACTURING METHOD OF THE SAME FUJIFILM CORP (JP) 2018-05-16 EP disclosed