Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.92 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 9/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.66 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL4914414 | 0.96 | ALDH1A1 (0.92) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL96291 | 0.96 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| Hydrochloric Acid SCHEMBL9456784 | 0.94 | ALDH1A1 (0.96) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL3181478 | 0.87 | ALDH1A1 (0.76) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL5566174 | 0.86 | ALDH1A1 (0.80) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL24068855 | 0.85 | ALDH1A1 (0.79) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL31432460 | 0.84 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL8356166 | 0.83 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL16381877 | 0.83 | ALDH1A1 (0.76) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL1566049 | 0.82 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567445-A | It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor | 坎塞拉有限公司 | 2018-01-09 | — | — | CN | disclosed |