Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21696330 | 0.89 | EPHX1 (0.46) | KDM4CMMP2EPHX1CNR1HTT | |
| SCHEMBL22992626 | 0.84 | EPHX1 (0.48) | KDM4CMMP2EPHX1CNR1HTT | |
| SCHEMBL18530841 | 0.84 | KDM4C (0.40) | KDM4CMMP1MMP2MMP3MMP9 | |
| SCHEMBL21946461 | 0.83 | KDM4C (0.42) | KDM4CMMP1MMP2MMP3MMP9 | |
| SCHEMBL24484549 | 0.83 | RIPK1 (0.38) | KDM4CMMP1MMP2MMP3MMP9 | |
| SCHEMBL20144634 | 0.82 | GGT1 (0.33) | KDM4CRIPK1POLBALDH1A1PAOX | |
| SCHEMBL18461405 | 0.82 | RIPK1 (0.32) | KDM4CRIPK1POLB | |
| SCHEMBL23519027 | 0.80 | EPHX1 (0.42) | KDM4CEPHX1CNR1POLBKMT2A | |
| SCHEMBL21696331 | 0.79 | RAB9A (0.38) | CNR1GAALMNAL3MBTL1 | |
| SCHEMBL5021618 | 0.79 | RIPK1 (0.48) | KDM4CMMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321279-B1 | EXENATIDE MODIFIER AND USE THEREOF | BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) | 2020-02-12 | — | — | EP | disclosed |
| EP-3321279-A1 | EXENATIDE MODIFIER AND USE THEREOF | Bright Gene Bio-Medical Technology Co., Ltd. (CN) | 2018-05-16 | — | — | EP | disclosed |