SCHEMBL20144855

SCHEMBL20144855

N[C@@H](CO)NC1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.40
ERAP2 Q6P179 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ADRB2 P07550 6/20 0.38
TP53 P04637 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460663 0.77 SHBG (0.44) ANPEPERAP2KDM4EADRB2ALDH1A1
SCHEMBL10939689 0.77 SHBG (0.44) ANPEPERAP2KDM4EADRB2ALDH1A1
SCHEMBL29223954 0.76 KDM4E (0.43) KDM4EADRB2TP53ALDH1A1HSD17B10
SCHEMBL28150548 0.76 EPHX1 (0.38) ANPEPERAP2KDM4EADRB2TP53
Hydrochloric Acid SCHEMBL11558216 0.76 SHBG (0.43) ANPEPERAP2KDM4EADRB2ALDH1A1
Ammonia Solution, Strong SCHEMBL29224616 0.74 KDM4E (0.41) ANPEPERAP2KDM4EADRB2TP53
SCHEMBL16949666 0.74 SHBG (0.41) ANPEPERAP2KDM4EADRB2ALDH1A1
SCHEMBL28080788 0.74 SMN1; SMN2 (0.39) KDM4EALDH1A1SMN1; SMN2
SCHEMBL11853895 0.73 EPHX1 (0.44) ANPEPERAP2KDM4ETP53ALDH1A1
SCHEMBL4628123 0.73 EPHX1 (0.43) KDM4EADRB2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448956-B1 SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS CENTRE NAT RECH SCIENT (FR) 2018-05-16 EP disclosed