SCHEMBL20146345

SCHEMBL20146345

CCCCC/C=C\C/C=C\CCCCCCCCN(CCCCCCCC/C=C\C/C=C\CCCCC)OC(=O)CN(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.50
ALDH1A1 P00352 5/20 0.48
PPARG P37231 5/20 0.48
KDM4E B2RXH2 4/20 0.48
F7 P08709 4/20 0.48
F3 P13726 4/20 0.48
PPARD Q03181 4/20 0.48
PPARA Q07869 4/20 0.48
FABP3 P05413 3/20 0.48
FFAR1 O14842 3/20 0.48
LMNA P02545 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP19A1 P11511 2/20 0.48
FABP4 P15090 2/20 0.48
HPGD P15428 2/20 0.48
ALOX15 P16050 2/20 0.48
PTGS1 P23219 2/20 0.48
NR4A2 P43354 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TDP1 Q9NUW8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20018254 0.86 CNR1 (0.51) CNR1ALDH1A1PPARGKDM4EF7
SCHEMBL20139394 0.86 CNR1 (0.51) CNR1ALDH1A1PPARGKDM4EF7
SCHEMBL24729116 0.84 FAAH (0.47) PPARGF7F3PPARDPPARA
SCHEMBL24728770 0.80 ALDH1A1 (0.51) ALDH1A1PPARGKDM4EF7F3
SCHEMBL21380053 0.80 MGLL (0.51) CNR1ALDH1A1PPARGKDM4EF7
SCHEMBL31685534 0.80 MGLL (0.54) CNR1ALDH1A1PPARGKDM4EF7
SCHEMBL24728762 0.79 CNR1 (0.55) CNR1ALDH1A1PPARGKDM4EF7
SCHEMBL29312920 0.79 CNR1 (0.50) CNR1ALDH1A1PPARGKDM4EF7
SCHEMBL27903374 0.79 CNR1 (0.62) CNR1ALDH1A1PPARGKDM4EF7
SCHEMBL10187821 0.78 ALDH1A1 (0.46) ALDH1A1PPARGKDM4EF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250162978-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2025-05-22 US claimed
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-12-26 US claimed
CN-110167922-B Cationic lipids for nucleic acid delivery and preparation thereof 特拉维夫大学拉莫特有限公司 2023-09-19 CN claimed
EP-3538515-B1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2022-07-20 EP claimed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US claimed
EP-3538515-B1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2022-07-20 EP disclosed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US disclosed
EP-3538515-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2019-09-18 EP disclosed
WO-2018087753-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2018-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof NPC1L1, NPC1, CETP CNR1 3460/4885ALDH1A1 3981/4885PPARG 1455/4885
US-20250162978-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP CNR1 3460/4885ALDH1A1 3981/4885PPARG 1455/4885
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP CNR1 3460/4885ALDH1A1 3981/4885PPARG 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.