Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144596 | 0.81 | MAPT (0.42) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL11125764 | 0.78 | FFAR1 (0.42) | FFAR1HTTGAAMAPT | |
| SCHEMBL5865593 | 0.78 | BCHE (0.55) | L3MBTL1FFAR1BCHEFFAR4LTA4H | |
| SCHEMBL10823669 | 0.77 | FFAR1 (0.45) | ALDH1A1KDM4ETDP1ATML3MBTL1 | |
| Diphenylether SCHEMBL11667270 | 0.77 | LTA4H (0.55) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL11696938 | 0.76 | LTA4H (0.53) | KDM4EMEN1KMT2ALTA4HSMN1; SMN2 | |
| SCHEMBL16768513 | 0.76 | THRB (0.58) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL16768511 | 0.76 | THRB (0.58) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL16768510 | 0.76 | THRB (0.58) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL29890954 | 0.75 | LTA4H (0.56) | LTA4HSMN1; SMN2HTTPPARGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077016-B1 | SOFT ACRYLIC MATERIALS WITH HIGH REFRACTIVE INDEX AND MINIMIZED GLISTENING | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |