SCHEMBL144596

SCHEMBL144596

C=CCOCCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
IDO1 P14902 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALOX15 P16050 2/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
AKR1B10 O60218 1/20 0.39
AKR1B1 P15121 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11125764 0.89 FFAR1 (0.42) MAPTIDO1TSHRTAAR1
SCHEMBL3438756 0.88 IDO1 (0.52) IDO1L3MBTL1TDP1HTR2A
SCHEMBL2009202 0.86 L3MBTL1 (0.47) IDO1L3MBTL1TDP1
SCHEMBL5865593 0.85 BCHE (0.55) MAPTRAB9AL3MBTL1SMN1; SMN2
SCHEMBL11917760 0.85 MEN1 (0.49) IDO1L3MBTL1HTR2A
SCHEMBL21517787 0.83 CA1 (0.41) CA1CA2CA9IDO1HCAR2
SCHEMBL3814937 0.82 TSHR (0.54) MAPTCA1CA2CA9IDO1
SCHEMBL8880401 0.82 ALDH1A1 (0.43) CA1CA2CA9IDO1HCAR2
SCHEMBL20146601 0.81 ALDH1A1 (0.43) MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2
SCHEMBL5347405 0.80 ESR1 (0.48) MAPTCA1CA2CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
EP-4096618-B1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2025-01-29 EP claimed
EP-4438065-A2 A MIXTURE COMPRISING 1,2-ALKANEDIOLS Symrise AG (DE) 2024-10-02 EP claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
US-20240050337-A1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2024-02-15 US claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-116490160-A A mixture containing 1, 2-alkanediol 西姆莱斯股份公司 2023-07-25 CN claimed
US-20230004023-A1 DIFFRACTIVE CONTACT LENSES ALCON INC. (CH) 2023-01-05 US claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
WO-2016049398-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
US-20160089464-A1 MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
US-20160090557-A1 SUBSTRATES COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
WO-2016049396-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
WO-2016049389-A1 MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
US-20160090555-A1 CLEANING AND/OR TREATMENT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
US-20160090556-A1 PRODUCTS COMPRISING MALODOR REDUCTION MATERIALS THE PROCTER & GAMBLE COMPANY 2016-03-31 US claimed
US-8426115-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-23 US claimed
US-20110033803-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-02-10 US claimed
US-20100159392-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-06-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA MAPT 2700/4885CA1 774/4885CA2 1793/4885
US-20240050337-A1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS OR10J3, OR51E2, MAL2 MAPT 867/4885CA1 3452/4885CA2 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.