SCHEMBL20146723

SCHEMBL20146723

CCCCCCN(CC(=O)OC(C)C)C(C)=O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA9 Q16790 2/20 0.37
CA2 P00918 1/20 0.37
MAPT P10636 2/20 0.37
MAPK1 P28482 1/20 0.37
CES2 O00748 1/20 0.36
FAAH O00519 5/20 0.36
DNM1 Q05193 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
MGLL Q99685 1/20 0.34
PRKCA P17252 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21667764 0.86 LMNA (0.43) LMNACA12CA1CA9CA2
SCHEMBL20125919 0.82 ZDHHC20 (0.54) LMNACA12CA1CA9CA2
SCHEMBL5929457 0.80 LMNA (0.58) LMNAMAPTMAPK1FAAHDNM1
SCHEMBL13746649 0.80 LMNA (0.58) LMNACA12CA1CA9MAPT
SCHEMBL26290428 0.79 ALDH1A1 (0.39) LMNAALDH1A1
SCHEMBL21667765 0.79 LMNA (0.41) LMNAMAPTALDH1A1
SCHEMBL12507254 0.78 LMNA (0.53) LMNACA12CA1CA9CA2
SCHEMBL2482724 0.76 CA12 (0.52) CA12CA1CA9CA2CES2
SCHEMBL1742678 0.76 CA12 (0.52) CA12CA1CA9CA2CES2
SCHEMBL2481657 0.76 CA12 (0.52) CA12CA1CA9CA2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3321333-A1 CURABLE COMPOSITION, CURABLE INK, ACCOMMODATING CONTAINER, IMAGE FORMING DEVICE, IMAGE FORMING METHOD, CURED MATTER, AND ACRYLAMIDE COMPOUND Ricoh Company Ltd. (JP) 2018-05-16 EP disclosed