Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043048 | 0.87 | RIPK1 (0.46) | GABRA1GABRB2RIPK1NPC1RAB9A | |
| SCHEMBL22043379 | 0.86 | GABRA1 (0.48) | GABRA1GABRB2RIPK1NPC1RAB9A | |
| SCHEMBL22043371 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2LMNAPOLB | |
| SCHEMBL19940597 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2PDK2MGLLPOLB | |
| SCHEMBL18243110 | 0.78 | GABRA1 (0.54) | GABRA1GABRB2LMNAPDK2MGLL | |
| SCHEMBL22043307 | 0.74 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL11806035 | 0.74 | GABRA1 (0.44) | GABRA1GABRB2RIPK1NPC1RAB9A | |
| SCHEMBL56747 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2RIPK1ATM | |
| SCHEMBL780023 | 0.73 | CA2 (0.37) | GABRA1GABRB2NPC1RAB9ALMNA | |
| SCHEMBL28262969 | 0.73 | GABRA1 (0.54) | GABRA1GABRB2LMNASMN1; SMN2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321954-A1 | VERY HIGH EFFICIENCY ORGANIC LIGHT EMITTING DEVICES BASED ON ELECTROPHOSPHORESCENCE | The Trustees of Princeton University (US) | 2018-05-16 | — | — | EP | disclosed |