Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CD69 | Q07108 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743196 | 0.87 | KMT2A (0.60) | KMT2ACD69ALOX15SMN1; SMN2TSHR | |
| SCHEMBL6745272 | 0.77 | SMN1; SMN2 (0.60) | KMT2ACD69ALOX15SMN1; SMN2TSHR | |
| SCHEMBL23111641 | 0.77 | PTGDR2 (0.57) | KMT2ACD69ALOX15SMN1; SMN2TSHR | |
| SCHEMBL2599614 | 0.74 | KMT2A (0.48) | KMT2ACD69SMN1; SMN2TSHRKDM4E | |
| SCHEMBL18668604 | 0.74 | CES2 (0.43) | KMT2ACD69 | |
| SCHEMBL9722723 | 0.71 | KMT2A (0.44) | KMT2ACD69ALOX15ALDH1A1 | |
| SCHEMBL257482 | 0.71 | L3MBTL1 (0.61) | KMT2AALOX15SMN1; SMN2LMNAKDM4E | |
| SCHEMBL29757370 | 0.71 | L3MBTL1 (0.61) | KMT2AALOX15SMN1; SMN2LMNAKDM4E | |
| SCHEMBL19983110 | 0.71 | KMT2A (0.40) | KMT2ACD69 | |
| SCHEMBL1145948 | 0.70 | KMT2A (0.62) | KMT2ACD69ALOX15SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569255-A1 | IMAGING METHOD OF AMPA RECEPTORS IN BRAIN OF PRIMATE ORGANISM, PROGRAM, DIAGNOSTIC AGENT, COMPANION DIAGNOSTIC AGENT, DRUG, SCREENING METHOD, INPUT TERMINAL, SERVER AND SYSTEM | Public University Corporation Yokohama City University (JP) | 2019-11-20 | — | — | EP | disclosed |
| EP-3321252-A1 | NOVEL COMPOUND THAT SPECIFICALLY BINDS TO AMPA RECEPTOR | Public University Corporation Yokohama City University (JP) | 2018-05-16 | — | — | EP | disclosed |