Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12288085 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL20147097 | 0.75 | KDM5A (0.40) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL6316378 | 0.68 | ALDH1A1 (0.47) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL17030224 | 0.67 | ALDH1A1 (0.48) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL20219195 | 0.65 | ALOX15 (0.42) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL28620707 | 0.63 | KDM5A (0.55) | MAPTALDH1A1CYP1A2KDM4EMAPK1 | |
| SCHEMBL10256830 | 0.63 | ALDH1A1 (0.58) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL24114961 | 0.62 | ALOX15 (0.42) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL29037593 | 0.61 | ALDH1A1 (0.56) | MAPTALDH1A1CYP1A2KDM4EALOX15 | |
| SCHEMBL11048618 | 0.61 | MAPK1 (0.55) | MAPTALDH1A1CYP1A2ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408749-B1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2018-05-16 | — | — | EP | disclosed |