Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628160 | 1.00 | KMT2A (0.56) | KMT2AKDM4ERAB9ANPC1CCR2 | |
| SCHEMBL2017811 | 0.89 | ALDH1A1 (0.50) | KMT2ARAB9ACCR2PKMP2RX7 | |
| SCHEMBL12628167 | 0.89 | ALDH1A1 (0.50) | KMT2ARAB9ACCR2PKMP2RX7 | |
| SCHEMBL2013288 | 0.89 | PKM (0.49) | KMT2ARAB9ATSHRPKMLMNA | |
| SCHEMBL12628169 | 0.89 | PKM (0.49) | KMT2ARAB9ATSHRPKMLMNA | |
| SCHEMBL2011504 | 0.88 | ALDH1A1 (0.54) | KMT2ARAB9APKM | |
| SCHEMBL12628159 | 0.88 | ALDH1A1 (0.54) | KMT2ARAB9APKM | |
| SCHEMBL12629088 | 0.87 | KMT2A (0.56) | KMT2ARAB9APKM | |
| SCHEMBL2011797 | 0.87 | KMT2A (0.56) | KMT2ARAB9APKM | |
| SCHEMBL2015115 | 0.85 | ALDH1A1 (0.51) | KMT2ATSHRPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |