Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598965 | 0.88 | MEN1 (0.51) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL697386 | 0.84 | KMT2A (0.48) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL1340134 | 0.83 | AOC3 (0.53) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL13067434 | 0.82 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2MAPK1AOC3ALDH1A1 | |
| SCHEMBL14539258 | 0.80 | PDCD1 (0.39) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL11212134 | 0.80 | AOC3 (0.42) | LMNASMN1; SMN2MAPK1AOC3ALDH1A1 | |
| SCHEMBL11300908 | 0.80 | AOC3 (0.46) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL30056339 | 0.80 | AOC3 (0.46) | PDCD1CD274PDE4APDE4BPDE4C | |
| Ether SCHEMBL27467122 | 0.79 | MEN1 (0.45) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL18674353 | 0.79 | PDCD1 (0.35) | PDCD1CD274PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134659-A1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2018-05-17 | — | — | US | disclosed |
| CN-1118448-C | Process for preparing benzyl-ethers | CHINOIN GYOGYSZER VEGY ZETI TE (HU) | 2003-08-20 | — | — | CN | disclosed |
| CN-1237954-A | Process for preparation of benzyl-ethers | CHINOIN GYOGYSZER VEGY ZETI TE (HU) | 1999-12-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134659-A1 | OXINDOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PARK7, OPRK1, COMT | PDCD1 1676/4885CD274 3708/4885PDE4A 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.