Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 3/20 | 0.40 |
| ▸ | CBFB | Q13951 | 2/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150815 | 1.00 | PDE2A (0.44) | PDE2ALMNAL3MBTL1ALDH1A1GPR3 | |
| SCHEMBL2828817 | 0.87 | LMNA (0.41) | PDE2ALMNAL3MBTL1ALDH1A1GPR3 | |
| SCHEMBL2828815 | 0.87 | LMNA (0.41) | PDE2ALMNAL3MBTL1ALDH1A1GPR3 | |
| SCHEMBL8692623 | 0.79 | AMY1A (0.59) | LMNAL3MBTL1ALDH1A1AMY1ACYP1A2 | |
| SCHEMBL8692626 | 0.79 | AMY1A (0.59) | LMNAL3MBTL1ALDH1A1AMY1ACYP1A2 | |
| SCHEMBL18502970 | 0.79 | AMY1A (0.59) | LMNAL3MBTL1ALDH1A1AMY1ACYP1A2 | |
| SCHEMBL2366445 | 0.77 | PDE2A (0.44) | PDE2ALMNAALDH1A1GPR3CBFB | |
| SCHEMBL2366206 | 0.77 | PDE2A (0.44) | PDE2ALMNAGPR3CBFBNPC1 | |
| SCHEMBL20148167 | 0.75 | HPGD (0.48) | LMNAL3MBTL1ALDH1A1AMY1ANPC1 | |
| SCHEMBL20151704 | 0.75 | HPGD (0.48) | LMNAL3MBTL1ALDH1A1AMY1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | FORUM PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | CHRNA7, CHRNA5, CHRNA2 | PDE2A 681/4885LMNA 2450/4885L3MBTL1 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.