SCHEMBL20148280

SCHEMBL20148280

CCCCCCCCCCCCOc1cc(C)cc(Br)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.47
BLM P54132 1/20 0.45
TP53 P04637 2/20 0.45
ALOX15 P16050 1/20 0.45
NR5A1 Q13285 1/20 0.44
TSHR P16473 2/20 0.44
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
GGPS1 O95749 1/20 0.40
SMPD1 P17405 3/20 0.40
LTA4H P09960 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12968212 0.93 DRD2 (0.41) PLA2G2ABLMTP53ALOX15NR5A1
SCHEMBL20148279 0.89 PLA2G2A (0.58) PLA2G2ABLMTP53NR5A1TSHR
SCHEMBL28405359 0.89 PLA2G2A (0.53) PLA2G2ABLMTP53NR5A1TSHR
SCHEMBL30464049 0.89 PLA2G2A (0.58) PLA2G2ABLMTP53NR5A1TSHR
SCHEMBL14732481 0.89 PLA2G2A (0.53) PLA2G2ABLMTP53NR5A1TSHR
SCHEMBL27932265 0.89 PLA2G2A (0.53) PLA2G2ABLMTP53NR5A1TSHR
SCHEMBL31344503 0.89 PLA2G2A (0.53) PLA2G2ABLMTP53NR5A1TSHR
SCHEMBL12440948 0.87 ELANE (0.43) TP53ALOX15LTA4HALDH1A1HTT
SCHEMBL1070543 0.87 TP53 (0.56) PLA2G2ABLMTP53ALOX15NR5A1
SCHEMBL12550198 0.87 PLA2G2A (0.59) PLA2G2ABLMTP53ALOX15NR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180205242-A1 CAPACITOR BASED POWER SYSTEM AND UNMANNED VEHICLE WITH THE CAPACITOR BASED POWER SYSTEM THEREOF CAPACITOR SCIENCES INCORPORATED 2018-07-19 US disclosed
US-20180137978-A1 HEIN ELECTRO-POLARIZABLE COMPOUND AND CAPACITOR THEREOF CAPACITOR SCIENCES INCORPORATED 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180137978-A1 HEIN ELECTRO-POLARIZABLE COMPOUND AND CAPACITOR THEREOF HCN2, KCNE1, KCNN2 PLA2G2A 2763/4885BLM 1032/4885TP53 3029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.