Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181733 | 0.92 | NPC1 (0.46) | NPC1RAB9AATMLMNAMAPK1 | |
| SCHEMBL22459501 | 0.87 | ALDH1A1 (0.52) | NPC1RAB9AATMLMNAMAPK1 | |
| SCHEMBL13703528 | 0.87 | ALDH1A1 (0.52) | NPC1RAB9ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL26508516 | 0.85 | GAA (0.59) | NPC1RAB9AATMLMNAMAPK1 | |
| SCHEMBL10180029 | 0.85 | HSD11B1 (0.56) | NPC1RAB9AATMLMNAMAPK1 | |
| SCHEMBL10106139 | 0.85 | GAA (0.59) | LMNASMN1; SMN2HSD11B1MAPTGAA | |
| SCHEMBL24637747 | 0.84 | MAPT (0.59) | NPC1RAB9ALMNAHSD11B1MAPT | |
| SCHEMBL12820521 | 0.84 | NPC1 (0.40) | NPC1RAB9AATMLMNAMAPK1 | |
| SCHEMBL14411334 | 0.84 | SHBG (0.53) | LMNAHSD11B1GAAESR1ESR2 | |
| SCHEMBL20148956 | 0.82 | HSD11B1 (0.41) | ATMLMNAHSD11B1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134844-A1 | Block Copolymer, Ion-Exchange Membrane And Method Of Preparing Block Copolymer | KOREA INSTITUTE OF ENERGY RESEARCH (KR) | 2018-05-17 | — | — | US | disclosed |