Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023725 | 0.81 | MEN1 (0.68) | CCR5MEN1KMT2ASLC18A3DRD2 | |
| SCHEMBL3598146 | 0.81 | MEN1 (0.68) | CCR5MEN1KMT2ASLC18A3DRD2 | |
| SCHEMBL22755777 | 0.81 | MEN1 (0.68) | CCR5MEN1KMT2ASLC18A3DRD2 | |
| SCHEMBL8844209 | 0.79 | MEN1 (0.57) | CCR5MEN1KMT2ASLC18A3DRD2 | |
| SCHEMBL28305302 | 0.79 | KDM4E (0.58) | MEN1KMT2ADRD2SIGMAR1DRD4 | |
| SCHEMBL6902946 | 0.79 | MEN1 (0.74) | CCR5MEN1KMT2ADRD2SIGMAR1 | |
| SCHEMBL19493714 | 0.77 | SLC18A3 (0.70) | CCR5MEN1KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL25890035 | 0.77 | ACHE (0.60) | CCR5MEN1KMT2A | |
| SCHEMBL20148958 | 0.77 | ACHE (0.60) | CCR5MEN1KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL22795424 | 0.77 | CNR2 (0.60) | SLC18A3DRD2SIGMAR1DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |