Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25492396 | 0.89 | TSHR (0.72) | TSHRADRA2AADRA1AKMT2AMAPT | |
| SCHEMBL12377230 | 0.82 | TSHR (0.62) | TSHRADRA2AADRA1AKMT2AMAPT | |
| SCHEMBL1036146 | 0.81 | TSHR (0.39) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL8476442 | 0.79 | TSHR (0.65) | TSHRADRA2AADRA1AKMT2AMAPT | |
| SCHEMBL5325979 | 0.79 | — | — | |
| SCHEMBL813658 | 0.79 | TSHR (0.75) | TSHRADRA2AADRA1AKMT2AMAPT | |
| SCHEMBL775807 | 0.77 | TSHR (0.62) | TSHRADRA2AADRA1AKMT2AMAPT | |
| SCHEMBL12846426 | 0.77 | TSHR (0.62) | TSHRADRA2AADRA1AKMT2AMAPT | |
| Ethylene SCHEMBL3383723 | 0.76 | DGKA (0.36) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL7622921 | 0.76 | TSHR (0.59) | TSHRADRA2AADRA1AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905711-B2 | Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal | VIFOR (INTERNATIONAL) LTD. (CH) | 2021-02-02 | — | — | US | disclosed |
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | VIFOR (INTERNATIONAL) LTD. (CH) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905711-B2 | Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal | KCNN3, KCNH3, KCNH2 | TSHR 2033/4885ADRA2A 904/4885ADRA1A 781/4885 |
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | KCNN3, KCNH3, KCNH2 | TSHR 2033/4885ADRA2A 904/4885ADRA1A 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.