Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18925630 | 0.76 | EIF4A3 (0.36) | PDE2AALDH1A1 | |
| SCHEMBL19151612 | 0.76 | ADRB2 (0.38) | ALDH1A1ADRB2CYP3A4HSD17B10ADRA2A | |
| SCHEMBL30977563 | 0.75 | ALDH1A1 (0.39) | ALDH1A1ADRB2CYP3A4HSD17B10ADRA2A | |
| SCHEMBL5151815 | 0.74 | AKR1C3 (0.40) | — | |
| SCHEMBL22000138 | 0.73 | ALDH1A1 (0.38) | PDE2AALDH1A1HSD17B10 | |
| SCHEMBL8281098 | 0.72 | ADRB2 (0.35) | PDE2AALDH1A1ADRB2CYP3A4HSD17B10 | |
| SCHEMBL28784595 | 0.71 | MAPT (0.35) | ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1099578 | 0.71 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL13532052 | 0.70 | RORC (0.41) | ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL27668309 | 0.69 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089373-A9 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018089373-A2 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |