SCHEMBL20149540

SCHEMBL20149540

COc1c(C)c(C)c(N)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18090612 0.86 HSD17B10 (0.32) HSD17B10
SCHEMBL6832953 0.79 HSD17B10 (0.44) HSD17B10
SCHEMBL24105794 0.77 IMPDH2 (0.39) HSD17B10
SCHEMBL10524905 0.77 HSD17B10 (0.38) HSD17B10
SCHEMBL7973474 0.75 HSD17B10 (0.41) HSD17B10
SCHEMBL9793464 0.74 ACHE (0.31)
SCHEMBL14877470 0.74 IMPDH2 (0.33) HSD17B10
SCHEMBL7627662 0.73 ACHE (0.33)
SCHEMBL18949191 0.72
SCHEMBL21170586 0.71 IMPDH2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089373-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-05-17 WO disclosed