SCHEMBL20149663

SCHEMBL20149663

CCCCCCN(CCCCCC)NC(=O)CCCN(C)C

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 6/20 0.60
HSP90AA1 P07900 1/20 0.46
FAAH O00519 3/20 0.44
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4C Q9H3R0 9/20 0.41
KDM4A O75164 8/20 0.41
KDM5A P29375 2/20 0.41
PHF8 Q9UPP1 2/20 0.41
KDM7A Q6ZMT4 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29255920 0.89 HSP90AA1 (0.57) DNM1HSP90AA1FAAHMEN1MAPK1
SCHEMBL29255877 0.89 HSP90AA1 (0.57) DNM1HSP90AA1FAAHMEN1MAPK1
SCHEMBL20138864 0.87 MEN1 (0.53) MEN1KMT2A
SCHEMBL21380041 0.84 DNM1 (0.45) DNM1THRATHRB
SCHEMBL28987996 0.83 HSP90AA1 (0.55) DNM1HSP90AA1FAAHMEN1MAPK1
SCHEMBL29174034 0.83 HSP90AA1 (0.55) DNM1HSP90AA1FAAHMEN1MAPK1
SCHEMBL17105834 0.83 HSP90AA1 (0.55) DNM1HSP90AA1FAAHMEN1MAPK1
SCHEMBL29174060 0.83 HSP90AA1 (0.55) DNM1HSP90AA1FAAHMEN1MAPK1
SCHEMBL20138868 0.82 LSS (0.44) DNM1FAAH
SCHEMBL25395101 0.81 HSP90AA1 (0.53) DNM1HSP90AA1FAAHMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018087753-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2018-05-17 WO disclosed