SCHEMBL20138864

SCHEMBL20138864

CCCCC/C=C\C/C=C\CCCCCCCCN(CCCCCCCC/C=C\C/C=C\CCCCC)NC(=O)CCCN(C)C

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CNR1 P21554 4/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
TRPV1 Q8NER1 1/20 0.52
MAPT P10636 1/20 0.52
ALOX12 P18054 1/20 0.52
BLM P54132 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20149663 0.87 DNM1 (0.60) MEN1KMT2A
SCHEMBL20138868 0.86 LSS (0.44) TRPV1
SCHEMBL20149580 0.84 DNM1 (0.54) CNR1ALDH1A1TRPV1MAPT
SCHEMBL20149581 0.84 DNM1 (0.48) TRPV1
SCHEMBL22046686 0.81 ALDH1A1 (0.61) CNR1ALDH1A1HPGDTDP1
SCHEMBL28005061 0.81 HRH3 (0.54) MEN1KMT2AMAPTBLMTDP1
SCHEMBL23499202 0.81 DNM1 (0.76) MEN1KMT2ACNR1ALDH1A1HPGD
SCHEMBL7031534 0.81 DNM1 (0.76) MEN1KMT2ACNR1ALDH1A1HPGD
SCHEMBL23499203 0.81 DNM1 (0.76) MEN1KMT2ACNR1ALDH1A1HPGD
SCHEMBL30540103 0.81 DNM1 (0.76) MEN1KMT2ACNR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250162978-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2025-05-22 US claimed
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-12-26 US claimed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US claimed
EP-3538515-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2019-09-18 EP claimed
WO-2018087753-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2018-05-17 WO claimed
EP-3538515-B1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF UNIV RAMOT (IL) 2022-07-20 EP disclosed
US-20220162552-A1 Nonviral Modification of T Cell Gene Expression Precision Nanosystems Inc. (CA) 2022-05-26 US disclosed
EP-3956459-A1 NONVIRAL MODIFICATION OF T CELL GENE EXPRESSION Precision Nanosystems Inc (CA) 2022-02-23 EP disclosed
WO-2020210901-A1 NONVIRAL MODIFICATION OF T CELL GENE EXPRESSION Precision Nanosystems Inc. (CA) 2020-10-22 WO disclosed
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US disclosed
WO-2018087753-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) 2018-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof NPC1L1, NPC1, CETP MEN1 1830/4885KMT2A 1852/4885CNR1 3460/4885
US-20250162978-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP MEN1 1830/4885KMT2A 1852/4885CNR1 3460/4885
US-20190292130-A1 CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF NPC1L1, NPC1, CETP MEN1 1830/4885KMT2A 1852/4885CNR1 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.