SCHEMBL20138868

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20138864	0.86	MEN1 (0.53)	TRPV1
	SCHEMBL20149580	0.86	DNM1 (0.54)	CNR2TRPV1DNM1FAAHEPHX2
	SCHEMBL20149663	0.82	DNM1 (0.60)	DNM1FAAH
	SCHEMBL20149581	0.81	DNM1 (0.48)	CNR2TRPV1DNM1EPHX2
	SCHEMBL24186699	0.80	DNM1 (0.56)	LSSTRPV1DNM1EPHX2LPAR1
	SCHEMBL8004466	0.77	DEGS1 (0.43)	LSSCNR2TRPV1FAAH
	SCHEMBL8004471	0.77	DEGS1 (0.43)	LSSCNR2TRPV1FAAH
	SCHEMBL15894688	0.77	DNM1 (0.50)	LSSTRPV1DNM1FAAHLPAR1
	SCHEMBL20143663	0.77	DNM1 (0.44)	LSSDNM1EPHX2LPAR1LPAR2
	SCHEMBL28005061	0.76	HRH3 (0.54)	FAAHEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.