Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542602 | 0.86 | ADORA2A (0.34) | PDE3BPDE3AHTR2BHTR5ATDO2 | |
| SCHEMBL24795852 | 0.81 | HTR2B (0.45) | PDE3BPDE3AHTR2BHTR5ATDO2 | |
| SCHEMBL17640479 | 0.78 | LIMK1 (0.45) | PDE3BPDE3AHTR2BHTR5ATDO2 | |
| SCHEMBL20137415 | 0.78 | MAPT (0.44) | L3MBTL1MAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL24118989 | 0.78 | CYP2A6 (0.44) | PDE3BPDE3ATDO2KDM4ENPC1 | |
| SCHEMBL11941250 | 0.78 | ESR1 (0.41) | PDE3BPDE3AHTR2BHTR5ATDO2 | |
| SCHEMBL25545911 | 0.78 | KDM4E (0.31) | HTR2BHTR5AKDM4ENPC1RAB9A | |
| SCHEMBL27057572 | 0.77 | PDE3B (0.35) | PDE3BPDE3AHTR2BHTR5ATDO2 | |
| SCHEMBL17640482 | 0.74 | LIMK1 (0.47) | PDE3BPDE3AHTR2BHTR5ATDO2 | |
| SCHEMBL23972156 | 0.74 | KDM4E (0.40) | PDE3BPDE3AHTR2BHTR5ATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354654-B1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2022-04-27 | — | — | EP | disclosed |
| US-20210343950-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2021-11-04 | — | — | US | disclosed |
| US-11069864-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200251669-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2020-08-06 | — | — | US | disclosed |
| US-10680188-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-06-09 | — | — | US | disclosed |
| EP-3354654-A2 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2018-08-01 | — | — | EP | disclosed |
| US-20180138427-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2018-05-17 | — | — | US | disclosed |
| US-20180138427-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10680188-B2 | Organic electroluminescent materials and devices | AOX1, OCIAD1, OCIAD2 | PDE3B 3066/4885PDE3A 3940/4885HTR2B 1824/4885 |
| US-20200251669-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | AOX1, OCIAD1, OCIAD2 | PDE3B 3066/4885PDE3A 3940/4885HTR2B 1824/4885 |
| US-20210343950-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | AOX1, OCIAD1, OCIAD2 | PDE3B 3066/4885PDE3A 3940/4885HTR2B 1824/4885 |
| US-20180138427-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | AOX1, OCIAD1, OCIAD2 | PDE3B 3066/4885PDE3A 3940/4885HTR2B 1824/4885 |
| US-11069864-B2 | Organic electroluminescent materials and devices | AOX1, OCIAD1, OCIAD2 | PDE3B 3066/4885PDE3A 3940/4885HTR2B 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.